Khaberni - A recent study has warned that excessive consumption of antioxidants, despite their health reputation, might carry unexpected effects extending to subsequent generations.
According to a report published on ScienceDaily based on research from Texas A&M University, high doses of popular supplements such as N-acetyl-L-cysteine and selenium may alter the DNA of sperm, reflecting on the development of embryos.
The results published in the journal Frontiers in Cell and Developmental Biology demonstrated that male mice receiving these supplements for six weeks had offspring suffering from significant changes in the shape of the skull and face, even though no health symptoms appeared on the fathers themselves.
Researchers point out that antioxidants are commonly used to reduce oxidative stress, especially among those exposed to stressors. However, when exceeding natural limits, the benefits can turn into harm.
It is believed that high doses affect "programming" of the sperm, leading to subtle changes in embryo development. Notably, the impact was more pronounced in female offspring, characterized by features such as closer-set eyes and smaller skull size.
Researchers warn that these morphological changes might reflect deeper disorders, as midfacial deformities are often associated with brain development. However, the study has not yet confirmed the presence of long-term neurological problems, calling for further research.
Balancing is key
Despite these findings, scientists confirm that the study was conducted on animal models, and thus, a similar impact cannot be definitively concluded for humans. However, it highlights the importance of moderation in consuming dietary supplements.
Researchers emphasize that doses exceeding 100% of the daily requirement can be concerning, especially for those planning to conceive, as over-consuming what is believed to be “beneficial” can carry uncalculated consequences.
The study points out that nutritional balance remains the critical factor, and that even common supplements are not without risks when used in high doses without a clear medical need.
