Khaberni - Researchers from Xi'an Jiaotong University in China have developed a new model for predicting the degree of aging of human organs, including the brain, which enables accurate assessment of aging levels in each organ.
Previous research primarily focused on the common traits of overall aging or the aging mechanisms in isolated organs, which made it difficult to decipher the distinct genetic patterns and molecular pathways associated with aging of different organs. This limitation hindered a deeper understanding of the nature of aging, as well as limited the development and implementation of precise strategies to combat it.
The study specifically identified (554) genes at risk of organ aging showing functions highly consistent with the physiological characteristics of their respective organs, revealing the underlying molecular mechanisms behind the aging process in each organ.
The new model exhibits strong and accurate predictive capabilities for assessing the aging state of organs across diverse population groups, laying the foundation for future mechanical research and clinical applications.
The researchers pointed out that the new model facilitates early screening for at-risk groups, clarifies the causal relationships between organ aging and chronic diseases, in addition to the impact of smoking on the aging of certain organs, providing crucial insights and evidence for disease prevention.
