Khaberni - A recent international study has revealed that a common hormonal procedure used in in vitro fertilization "IVF" does not achieve the desired benefit.
According to a report in "Medical Xpress", the use of hCG hormone inside the uterus before embryo transfer does not increase the chances of pregnancy or childbirth.
Research indicates that this procedure was introduced years ago as a means to enhance embryo implantation, and has been widely used in many countries, despite varying scientific evidence about its effectiveness.
However, the new study relied on a precise analysis of raw data from clinical trials, rather than just published results, which gave it higher accuracy in evaluation.
Decisive results across different groups
The analysis included data from 2244 patients from seven high-quality trials, out of 28 studies reviewed.
The results showed no improvement in clinical pregnancy rates or live birth rates, regardless of the type of embryo transfer, the doses used, or the patient characteristics.
Previous reviews had suggested a potential benefit of this procedure, but researchers found that many of those studies did not meet quality standards, or relied on unreliable data. When reanalyzing the verifiable data, the positive effect completely disappeared.
Additional burden without return
Although the cost of this procedure may seem relatively limited, its repetition in multiple treatment cycles could increase the financial and psychological burden on patients, without any real benefit, and some clinics may offer it as an additional option without sufficient clarification of its effectiveness.
Researchers believe that these results highlight a broader problem in fertility medicine, where some procedures are adopted based on insufficient evidence. They emphasize the importance of relying on individual patient data to get a clearer picture of what works and what does not.
This study indicates that the use of this hormone is not associated with improved outcomes, meaning that its presence in treatment protocols does not add real value. These results also clarify that some "additions" in fertility treatments may be unnecessary, highlighting the importance of making treatment decisions based on strong scientific evidence, not assumptions or unconfirmed results.
