Khaberni - Some of us remember that we had more energy in our twenties, and as we reach our forties, this feeling of ease often disappears; ridding fatigue becomes more challenging.
Researchers confirm that the forties are often the most exhausting decades, not because we are old, but because many minor biological changes coincide with the peak demands of life.
According to a scientific article published on "Science Alert", in the beginning of adulthood, many body systems reach their peak simultaneously, and muscle mass is at its highest levels, even without deliberate training. As an active metabolic tissue, muscles help regulate blood sugar levels and reduce the effort required for daily activities. At the cellular level, mitochondria - the organelles responsible for converting food into usable energy - are more numerous and efficient, sleep becomes deeper, and hormonal rhythms become more stable. Cortisol, known as the stress hormone, along with melatonin, growth hormone, and sex hormones, have regular daily patterns, which makes energy more stable throughout the day.
But with mid-life, slight changes begin to appear, and muscle mass decreases from the late thirties onwards unless exercising to maintain it. A decrease in muscle mass means that daily movement consumes more energy, even if you are not consciously aware of it. The mitochondria still produce energy, but with less efficiency. Sleep also changes to become fragmented, and less deep sleep means less recovery. Fatigue becomes cumulative rather than incidental.
Hormones in midlife don't disappear; they fluctuate, particularly in women, disrupting body temperature regulation, sleep timings, and energy rhythms. Then comes the brain; midlife is a period of peak cognitive and emotional effort: leadership, responsibility, vigilance, caring roles, and multitasking mentally exhaust energy as effectively as physical labor.
For this reason, the forties can be extremely exhausting, and biological efficiency begins to change at the moment when demand is at its peak. Late life is often regarded as a continuation of the decline of midlife; however, many report something different.
However, later and into the sixties, hormonal systems often stabilize after transition periods; life roles might become simpler, cognitive effort can decrease, and experience replaces constantly active decision-making. Sleep doesn't necessarily deteriorate with advancing age; when stress decreases and daily routines are preserved, sleep efficiency improves, even if the total sleep time is shorter.
Most importantly, muscles and mitochondria continue to adapt remarkably with age. Strength training exercises in individuals in their sixties, seventies, and beyond can restore strength, improve metabolic health, and increase self-energy within months.



