Khaberni - A scientific study has shown that certain medications frequently prescribed to treat conditions such as bladder disorders, Parkinson's disease, and depression may increase the risk of dementia.
The research, conducted by researchers at the University of Nottingham, revealed an approximately 50% increased risk of dementia in patients over the age of 55 who had taken strong anticholinergic drugs daily for 3 years or more.
Anticholinergic drugs
Anticholinergic drugs, which help muscle contractions and relaxation by inhibiting acetylcholine, a chemical that transmits signals in the nervous system, are commonly used to treat a range of conditions, including chronic obstructive pulmonary disease, bladder disorders, allergies, gastrointestinal disorders, and Parkinson’s disease symptoms.
According to "Souriya Life", while these drugs may cause short-term side effects such as mental confusion and memory loss, the new study sought to explore their long-term use impact.
Under the supervision of Dr. Carol Coupland, the research examined medical records of over 58,000 patients diagnosed with dementia and 225,000 patients who were not diagnosed with it.
All participants were aged 55 years and older, during the period between 2004 and 2016.
Parkinson’s medications
Coupland said, "Our study adds more evidence to the potential risks associated with strong anticholinergic drugs, particularly antidepressants, muscarine antagonists for bladder treatment, Parkinson’s medications, and epilepsy drugs."
However, it is important that patients who are taking these types of medications do not suddenly stop taking them, as this could be more harmful. If patients have any concerns, they should discuss them with their doctor to consider the pros and cons of the treatment they are receiving."
